Diagnosis Pcr= 57% in August 2018.
Treatment 100 mg sprycel
After 1 month pcr= 17 IS
3 months = 0.19 IS, Fish= no phil detected
6 months = 0 .16 IS
I was a little surprised with my latest PCR as it only went down .19 to .16 in the last three months. Has any one else had this drastic decrease in getting to .1. Would this warrant further tested for mutations or medication change?
No I don't think this result warrants any change. Trend is still downward, and most of us experienced a plateau in the reduction in BCR ABL. See what the next two results are. There's a little bit of me wonders if your three month result was correct - that's a huge reduction from dx. Keep taking the pills and I absolutely expect you to be at 0.1% by 12 months. If you're not it may well not matter - it took me 18 months to get to MMR (before the 0.1% target at 12 months was in place). I am now 4 months into trying TFR.
Can working out before a blood draw raise your PCR? I am very active and ran a 5 k the morning of my draw.
Yes. https://www.cmlsupport.org.uk/article/bcr-abl1-levels-increase-periphera...
"The BCR-ABL1 transcript level increased significantly following exercise"
Here is a link to the full article: https://sci-hub.se/10.3109/00365513.2010.521981
